By A G Schaake; J C Turner; University of Waikato. Dept. of Mathematics and Statistics
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NRW, 2475 (1974). Westdeutscher Verlag, Opladen 13. A. A. Naturwiss. , in press 14. A. and Renwrantz, L. Bioi. Zentralbl. 94, 205 (1975) 15. A. and Uhlenbruck, G. Immunology 25, 649 (1973) 16. , Uhlenbruck, G. and Salfner, B. Z. Immun. -Forsch. 148, 330 (1975) 17. E. and Potter, M. Carbohydrate Res. 30, 409 (1973) 18. Glaudemans, C. P. , Zissis, E. and Jolley, M. E. Carbohydrate Res. 40, 129 (1974) 19. Kakoma, I. and Kinyanjui, Res. vet. Sci. 17, 397 (1974) 20. Grappel, S. , Blank, F. and Bishop, T.
J. Invert. , 8: 478 (1966). The authors acknowledge the technical assistance of Elizabeth Keough and Nancy Williams in the first part of this study. S. S. Public Health Service and the Faculty Research Committee, University of California, Santa Barbara. , VALEMBOIS, P. and DU PASQUIER, L. Laboratoire de Zoologie A de l'Universite de Bordeaux et Centre de Morphologie Experimentale du CNRS~ Avenue des Facultes, 33405 TALENCE (France); Basel Institute for Immunology, Grenzacherstrasse 487, CH 4058 BASEL (Switzerland) INTRODUCTION There are several reasons to believe that rejection of both allogenic and xenogenic tissues by earthworms is due to an active immune response: a second graft from a same donor to a same receptor is more actively rejected (1); graft immunity can be transfered by coelomic cells from a sensitized animal to a non sensitized one (2).
Only mild differences were noticed when comparing first and second grafts. We have then studied the morphological features of the stimulated cells by the mean of autoradiography. Both autoradiographies on cells smeared on slides and in high resolution have shown that labelled cells could be arranged in two size categories: leukocytes with a diameter below 10 pm and leukocytes above 10 pm in diameter. Cells of the first group had a large nucleous and many free ribosomes in most of the available cytoplasm.