By Francis Knowles (auth.), Sir Francis Knowles F.R.S., Lutz Vollrath (eds.)
This quantity marks the top of two decades of neurosecretion within which there have been 5 symposia, particularly Naples (1953), Lund (1957), Bristol (1961), Strasbourg (1966), and Kiel (1970). compared to those symposia a really huge variety of papers have been learn at this the 6th symposium, in London, and for fiscal purposes it has now not been attainable to submit all of the papers in extenso. The editors have hence been obliged to adopt the unenviable paintings of choice, a job made the entire tougher by means of the excel lence and value of contributions of the symposium. We felt that it was once of the maximum significance at this second within the historical past of neurosecretion to offer as whole an image as attainable of the current kingdom of the topic on the subject of the prior and possibilities for the longer term. we have now for this reason given a few choice to papers with a robust overview aspect, examine papers in parts of present value and contributions which care for lately constructed recommendations with promise for the long run. we now have extra over tried to strike a few stability among the various parts of analysis on neurosecretion in order that the amount as an entire can be of curiosity to the final reader, and that he'll locate in it a pretty coherent trend of suggestion which demonstrates neurosecretion because the ultimate neuroendocrine pathway. now we have tried a undeniable measure of uniformity of spelling, symbols, etc.
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Extra info for Neurosecretion — The Final Neuroendocrine Pathway: VI International Symposium on Neurosecretion, London 1973
Example text
Brain Res. 20, 462-466 (1970). : The secretory cycle of supraoptic neurons in the rat. A structural-functional correlation. Z. Zellforsch. 73, 414-431 (1966). Immunohistochemistry of Vasopressin: Study of the Hypothalamo-Neurohypophysial System of Normal, Dehydrated and Hypophysectomized Rats A. BURLET, J. MARCHETTI, and J. R. Sciences Medicales, Nancy-Cedex (France) After the initial findings of Bargmann (1949), using Gomori chrome-alumhaematoxylin, several histochemical methods have been proposed for demonstrating the neurosecretory material of the mammalian hypothalamo-neurohypophysial system (HNHS)-(see References in GABE, 1966).
Effects on the isolated neurohypophysis of agents which affect the membrane permeability to calcium. J. Physiol. ) 231, 96~98P (1973). : Exocytose am Hinterlappen der Hypophyse. Z. Zellforsch. 123, 47~54 (1972). , Douglas, W. : Micropinocytotic origin of coated and smooth microvesicles ("synaptic vesicles") in neurosecretory terminals of posterior pituitary glands demonstrated by incorporation of horseradish peroxidase. ) 232, 341~342 (1971). : Secretion-dependent endocytosis in the rat neurohypophysis.
Calcium is that low temperature may stimulate exocytosis by causing a redistribution of intra-cellular calcium. , 1973), indicate that hormone release from actively secreting neurohypophyses is accompanied by membrane phenomena which would be unnecessary if secretion occurred by simple diffusion of hormone molecules through the plasma membrane; rather, they strongly favour the view that hormones (and neurophysins) contained within the neurosecretory granules are expelled to the extra-cellular space in an exo-endocytotic process.