By Yashwant Pathak, Simon Benita
Content material:
Chapter 1 Antibody?Mediated Drug supply platforms: normal evaluation and functions (pages 1–12): Navdeep Kaur, Karthikeyan Subramani and Yashwant Pathak
Chapter 2 Immunoliposomes for Cardiovascular concentrating on (pages 13–33): Tatyana Levchenko, William Hartner and Vladimir P. Torchilin
Chapter three Antibody?Mediated Drug supply structures for Breast melanoma Therapeutics (pages 35–55): Leonor Munoz Alcivar and Yashwant Pathak
Chapter four improvement of Immunonconjugates for in Vivo supply: melanoma prognosis, Imaging, and remedy (pages 57–81): Arutselvan Natarajan
Chapter five Mathematical versions of Anti?TNF treatments and their Correlation with Tuberculosis (pages 83–104): Simeone Marino, Mohammad Fallahi?Sichani, Jennifer J. Linderman and Denise E. Kirschner
Chapter 6 particular Nanoparticles in Radiotherapy (pages 105–128): Misty Muscarella and Yashwant Pathak
Chapter 7 Electrically?Enhanced supply of substances and Conjugates for melanoma remedy (pages 129–143): Arutselvan Natarajan, Luca Campana and Raji Sundararajan
Chapter eight Characterization of Monoclonal Antibody versions and Glycosylation (pages 145–167): Ting Zheng, Srinivasa Rao, Jeff Rohrer and Chris Pohl
Chapter nine Antibody?Mediated Drug supply process for Lymphatic focusing on remedy (pages 169–190): Fang Wu, Hong Ding and Zhirong Zhang
Chapter 10 equipment for Nanoparticle Conjugation to Monoclonal Antibodies (pages 191–207): Junling Li and Chin ok. Ng
Chapter eleven Single?Use structures in Animal Cell–Based Bioproduction (pages 209–228): William G. Whitford
Chapter 12 Immunoliposomes for particular Drug supply (pages 229–266): Manuela Calin
Chapter thirteen Gene remedy concentrating on Kidney illnesses: Routes and autos (pages 267–277): Yoshitaka Isaka, Yoshitsugu Takabatake and Hiromi Rakugi
Chapter 14 Detection of Antibodies to Poly(Ethylene Glycol) Polymers utilizing Double?Antigen?Bridging Immunogenicity ELISA (pages 279–290): Yijuan Liu, Helen Reidler, Jing Pan, David Milunic, Dujie Qin, Dave Chen, Yli Remo Vallejo and Ray Yin
Chapter 15 Antibodies in Nanomedicine and Microimaging equipment (pages 291–349): Rakesh Sharma
Chapter sixteen equipment for Polymeric Nanoparticle Conjugation to Monoclonal Antibodies (pages 351–363): Uyen Minh Le, Hieu Tran and Yashwant Pathak
Chapter 17 Plant?Derived Antibodies for tutorial, business, and healing functions (pages 365–381): Slavko Komarnytsky and Nikolai Borisjuk
Chapter 18 Monoclonal Antibodies as Biopharmaceuticals (pages 383–389): Girish J. Kotwal
Chapter 19 Pulmonary concentrating on of Nanoparticles and Monoclonal Antibodies (pages 391–405): Weiyuan Chang
Chapter 20 Antibody?Mediated Arthritis and New healing Avenues (pages 407–426): Kutty Selva Nandakumar
Chapter 21 Immunonanoparticles for Nuclear Imaging and Radiotherapy (pages 427–456): Oren Giladi and Simon Benita
Chapter 22 Monoclonal Antibodies within the remedy of bronchial asthma (pages 457–472): Glenn J. Whelan
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Extra info for Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications
Example text
2010). Research and development of next generation of antibody-based therapeutics. Acta Pharmacol. Sin. 31(9); 198–207. 3. html. 4. aspx. 5. com/a-to-z-guides/immunoglobulins. 6. html. 7. org/wiki/IgE. REFERENCES 11 8. Steinitz, M. (2009). Three decades of human monoclonal antibodies: past, present and future developments. Hum. Antibodies. 18(1–2); 1–10. 9. Parker, D. C. (1993). T cell-dependent B cell activation. Annu. Rev. Immunol . 11, 331–360. 10. pdf. 11. org/wiki/B_cell. 12. org/wiki/Antibody.
Opin. Chem. Biol . 14(4); 529–537. 22. com/wt/page/other. 23. html. 24. &vmview=abst_detail_view_&confID=73&abstractID=30405. 25. shtml. 26. shtml. 27. shtml. 28. shtml. 29. shtml. 30. shtml. 31. com/wt/page/im388. 32. com/wt/page/sar3419. 33. com/wt/page/IMGN901b. 34. com/wt/page/trastuzumab_DM1. 35. com/wt/page/cancer. 36. com/gene/pipeline/status/oncology/anti-cd22/. 37. html. 38. Robinson, M. , Plascjak, P. , Hodge, K. , Yuan, Q. , Marks, J. , Waldmann, T. , Brechbiel, M. , Adams, G. P. (2008).
Market. 7 billion in 2015, according to DatamonitorPlc, a London-based health information firm [3]. 2 ANTIBODIES Antibodies (also known as immunoglobulins) are proteinacious in nature and are produced in response to an invasion of foreign substances in the body called antigens. 1 Structure of Antibodies Antibodies are heavy (∼150 kDa), Y-shaped glycoproteins composed of four polypeptide chains: two long heavy or H chains and two short light or L chains. The end of light and heavy chains together constitutes a variable region (also known as antigen-binding site) consisting of 110 to 130 amino acids.