Pediatric Oncology: A Comprehensive Guide by Professor Dr. Paul Imbach, Dr. Thomas Kühne, Robert J.

By Professor Dr. Paul Imbach, Dr. Thomas Kühne, Robert J. Arceci (eds.)

Pediatric Oncology Compendium – guidance for scientific practice!

Compact presentation of regularly encountered pediatric oncological ailments and their care.

Pediatric oncology at a glance!

Optimal orientation ensured by means of transparent and constant structure and concise, lucid type.

Pediatric oncology is teamwork!

Fundamental proof for all these fascinated with remedy – medical institution physicians, expert nurses, psychooncologists and physiotherapists, relations medical professionals and pediatricians.

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This procedure seems equally successful to prophylactic CNS irradiation. g. g. daunorubicin) lead to approximately 70% remission (less than 5% blasts in bone marrow) within 4–6 weeks and no other evidence of leukemias  Other combinations such as 6-thioguanine, etoposide or the use of other anthracyclines (idarubicin, rubidomycin) and mitoxantrone result in remissions up to 85%  Supportive therapy and prophylaxis (antibacterial, antiviral, antifungal) and the use of hematopoietic growth factors reduce morbidity and lethality.

Pneumocystis carinii), virus or fungal infection treatment should be according to resistance analysis of the causative microbe – In viral infections antiviral agents, often in combination with addition of intravenous application of immunoglobulins in cases of low serum IgG level – When signs of interstitial pneumonia occur: high-dose trimethoprimsulfamethoxazole: 20 mg trimethoprim/kg body weight Relapse  Usually the same pheno- and genotype of ALL as at initial diagnosis  Rarely another cell line of leukemia ( a lineage switch), especially in patients with initial biclonal leukemia.

5 × 109/l): blood culture analysis and immediate start of broad-spectrum antibiotics – In infection with Pseudomonas, E. , Pneumocystis carinii), virus or fungal infection treatment should be according to resistance analysis of the causative microbe – In viral infections antiviral agents, often in combination with addition of intravenous application of immunoglobulins in cases of low serum IgG level – When signs of interstitial pneumonia occur: high-dose trimethoprimsulfamethoxazole: 20 mg trimethoprim/kg body weight Relapse  Usually the same pheno- and genotype of ALL as at initial diagnosis  Rarely another cell line of leukemia ( a lineage switch), especially in patients with initial biclonal leukemia.

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