By Ray Paton (auth.), Mike Holcombe, Ray Paton (eds.)
Signalling and Communication: An advent to part 1; R. Paton. a few features of hole Junction Dynamics in Embryonic platforms; S.Baigent, et al. genuine Time Processing of Nerve indications for Controlling a Limb Prostheses; M. Bodgan, W. Rosentiel. Stimulus-Secretion Coupling in Pancreatic beta-Cells defined by way of Chay's Store-Operated version; T.R. Chay. in the direction of Computational types of Chemotaxis in Escherichia Coli; L. Clarke, R.C. Paton. 3 Modes of Calcium-Induced Calcium free up (CICR) in Neurons; D.D. Friel. Theta-Neuron, a One Dimensional Spiking version that Reproduces inVitro and in Vivo Spiking features of Cortical Neurons; B.S.Gutkin, G.B. Ermentrout.Computation and Information: An advent to part 2; R. Paton. Morphomechanical suggestions in Embryonic improvement; L.V. Beloussov. info Processing in Computational Tissues;M.H. Butler, et al. Semiotics of complicated platforms: A Hierarchical Notation for the Mathematical constitution of a unmarried mobile; J.L.R. Chandler. Localization and Nonlocality in Computation; R.Cottam, et al. Mining the Gene Expression Matrix: Inferring Gene Relationships from huge Scale Gene Expression info; P. D'haeseleer,et al. Epilogue-Concluding Discussions; M. Holcombe. 18 extra Chapters. Index.
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Extra resources for Information Processing in Cells and Tissues
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This is why single b-cells burst very slowly (Smith, Aschcroft & Rorsman, 1990). DISCUSSION The central assumption in the store-operated model is that a Hodgkin-Huxley type mechanism is inappropriate to describe slowly bursting b-cells. In this cell, the slow cyclic variation of [Ca2+]IUm drives electrical bursting and [Ca2+]j oscillation. Using this model, I showed how the intracellular calcium store participates encoding the frequency of bursting (see Fig. 7). What is the significance of frequency encoding in physiology?
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The present paper explains how the intracellular calcium stores communicate with the ion channels in the plasma membrane to generate these interesting bursting patterns. My explanation is based on Chay's store-operated model (Chay, 1995, Chay, 1997], which assumes that the calcium concentration in the lumen of 29 the calcium store, [Ca2+]lum' drives electrical bursting and the [Ca2+]j oscillation. The dynamic change of [Ca2 +]lum' in turn, is controlled by the neurotransmitters and hormones that influence the PI- and AC-signalling pathways.