By Phyllis J. Kanki (auth.), Phyllis Kanki, Darrell Jay Grimes (eds.)
Infectious illnesses: chosen Entries from the Encyclopedia of Sustainability technological know-how and Technology offers authoritative, peer-reviewed contributions from best specialists on quite a lot of significant infectious illnesses of worldwide significance. Infectious ailments account for greater than 17 million deaths every year around the world. whereas smooth drugs and expertise have reduced the specter of lots of those pathogens in high-income international locations, the ubiquitous threats of re-emerging infections, inhabitants mobility, normal failures, and pathogen genetic variability are yet a few of the purposes for the dynamic probability of this vast classification of dangers to human well-being.
An essential source for college kids and scientists, the amount additionally covers a number of the new applied sciences presently less than improvement for infectious illness prevention, remedy, and eradication. The better a part of the infectious affliction burden continues to be within the tropics, the place low and middle-income international locations lack the assets, infrastructure, and well-being platforms to mount or maintain regulate efforts. Many contributions describe the efforts of the clinical study neighborhood and overseas donor businesses to accomplish the built-in pursuits of vigilant surveillance, greater and comparatively cheap diagnostics, and therapy for sustainable ailment control.
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Additional info for Infectious Diseases: Selected Entries from the Encyclopedia of Sustainability Science and Technology
Example text
Education and behavior change are critical components of prevention methods, and provision is often most effective when provided by community groups. In the early 1980s in the USA, pioneer groups such as the San Francisco AIDS Foundation, Gay Men’s Crisis in New York, and AIDS Project Los Angeles demonstrated the role of education in promoting safer sex practices among gay and bisexual men [70]. Recent increases in new infections in young gay men in North America and Europe are of concern and suggest the need to enhance prevention efforts [2, 63].
J Biol Chem 285(9):6161–6169 42. Johansson P et al (2008) Inhibition of the fungal fatty acid synthase type I multienzyme complex. Proc Natl Acad Sci USA 105(35):12803–12808 43. Nishida I, Kawaguchi A, Yamada M (1986) Effect of thiolactomycin on the individual enzymes of the fatty acid synthase system in Escherichia coli. J Biochem 99(5):1447–1454 44. McFadden JM et al (2005) Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase. J Med Chem 48(4):946–961 45.
Although HIV-2 can cause AIDS, it has a distinct epidemiology, lower rate of transmission, and slower progression to disease. Rate describing the number of new cases of disease occurring within a given time period, expressed as new cases per person-time. An enzyme found in retroviruses including HIV that permits the reverse transcribed viral DNA to be integrated into the infected cell’s DNA. Integrase is an enzyme encoded by the polymerase gene of HIV. A class of ART drugs that blocks the viral integrase the enzyme HIV uses to integrate its genetic material into its target host cell DNA.