By J. Dyerberg (auth.), R. De Caterina, S. D. Kristensen, E. B. Schmidt (eds.)
Fish Oil and Vascular Disease covers the main proper facets of fish oil (n-3 polyunsaturated fatty acids) on vascular illness. The textual content contains historical past epidemiological details, dietary facets, results on a number of organic capabilities, in all likelihood mediating the results on atherosclerosis and its scientific sequelae, and provides an intensive insurance of the results upon blood strain. The publication is split into 3 major sections. the 1st bargains with the epidemiological and dietary history of the n-3 PUFA and their relation to cardiovascular disease.
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Example text
C i "iii ,.... 100 u. 0 "iii ,.... 20 u. 0 Q) Q) 0.. a... OS 30 r------1 0.. a... 6 Basal AA L__NS__j L__ NS __j cO 10 ~ cb 0 Basal L Saphenous vein luminal surface Saphenous vein NS r------1 ~ 30 c «i "E. 01 C\J E ~ c i 0.. :: 0 2 a... 01__j L__ L Fig . 2. 8 g DHA/day for 28 days)(white columns). Results are expressed as mean ± SEM. A clear increase in prostacyclin production is evident in all conditions from patients after fish oil treatment (reprinted from Circulation,5 with permission) . equivalent to what is obtainable in platelets from serum thromboxane measurements.
1989; 225Suppl1: 133-139 8. B. WEKSLER Division of Hematology-Oncology, Department of Medicine, Cornell University Medical College, New York, USA Involvement of Activated Blood Cells in Atherosclerosis The development of an atheromatous plaque in an artery is a complex process requiring interactions of the vascular wall not only with plasma factors such as lipoproteins but also with multiple cellular elements, the most relevant being platelets and leukocytes. 1 The endothelial lining of an artery normally displays multiple antithrombotic mechanisms that promote blood flow and inhibit clot formation (Tab.
KRISTENSEN University Department of Cardiology, Skejby Hospital, Aarhus N, Denmark Two recent controlled studies have shown that dietary supplementation with n3 polyunsaturated fatty acids (PUFA) causes a decrease in blood pressure in patients with mild hypertension. 1•2 The purpose of this paper is to review the epidemiological data on the relation between fish intake and blood pressure. The evidence arises from three different lines of research: 1. studies on blood pressure values in Eskimos; 2.