By Francis J. D'Addario (Auth.)
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1986. 15. Flecknell PA, Mitchell M. Midazolam and fentanyl-tluanisone: assessment of anesthetic efects in laboratory rodents and rabbits. Lab Anim 18:143-146, 1984. 16. Whelan G, Flecknell PA. The use of etorphine/methotrimeprazine and midazolam as an anaesthetic technique in laboratory rats and mice. Lab Anim 28:70-77, 1994. 17. Zuurbier CJ, Emons VM, Ince C. Hemodynamics of anesthctized ventilated mouse models: aspects of anesthetics, t1uid support, and strain. T Physiol( Heart Cire Physiol )282:H2099-H2105,2002.
D. 4 mm). We used a fixed insertion length of 5 mm for all animals (C57BI6). Patency strategies Patency strategies are mainly focused on preventing thrombi from blocking the cannula. Most patency studies in this respect were done in humans 3,4,7,14,18. The formation of a thrombus following catheter insertion is initiated by a decreased blood flow, increased tendency of blood to 20 Physiological Genomics of the Critically III Mouse coagulate and alternation in vessel wall integrity. The use of soft cannula material will minimize trauma to the vascular wall.
Hemodynamics of anesthctized ventilated mouse models: aspects of anesthetics, t1uid support, and strain. T Physiol( Heart Cire Physiol )282:H2099-H2105,2002. 18. Schwarte LA, Zuurbier CJ, and Inee C. Mechanical ventilation of mice. Bas Res Cardiol 95: 510-520, 2000. 19. Kramer K, van Acker SA, Voss HP, et al. Use of telemetry to record electrocardiogram and heart in freely moving mice. J Pharmacol Toxicol Methods 30:209-215, 1993. Furukawa S, MacLennan MJ, and Keller BB. Hemodynamic response to anesthesia in pregnant and nonpregnant ICR mice.