Contextualizing Systems Biology: Presuppositions and by Martin Döring, Imme Petersen, Anne Brüninghaus, Regine

By Martin Döring, Imme Petersen, Anne Brüninghaus, Regine Kollek

This collective monograph goals at contributing to a much better realizing of the epistemic presumptions, sociocultural implications and traditionally backgrounds of the newly rising and at present increasing technique of platforms biology. In doing so, it bargains empirically grounded, important and reflexive information regarding a paradigmatic shift within the biosciences for a variety of scientists operating within the interdisciplinary parts of structures biology, man made biology, molecular biology, biology, the philosophy of technological know-how, the sociology of technological know-how and clinical wisdom, technology and know-how stories, know-how review and so forth. The authors of this monograph percentage the theoretical methodological premise that technology is a culturally and socially embedded perform which characterizes our tradition as a systematic one and even as attracts its cutting edge strength from its socio-cultural context. This dialectic courting lies on the middle of the present improvement of structures biology that's conceived as a so-called successor of ‘-omics’ examine and brought on via high-throughput info applied sciences. while a necessity for a holistic conceptualization of complicated organic methods emerges. The identify Contextualizing structures Biology means that this publication analyzes the advance and creation of platforms biology from diversified theoretical and methodological views. We examine various contexts starting from the research of cognitive contexts (such as uncomplicated theoretical ideas) to regulative contexts (policies) to the concrete software of a platforms biology within the socio-scientific context of a ecu examine venture. In empirically reading those diverse and interrelated layers and dimensions of platforms biology, the scope of the e-book is going past current makes an attempt to enquire the arrival of latest ways within the organic sciences because it frames and assesses structures biology from an interdisciplinary and built-in perspective.

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Extra info for Contextualizing Systems Biology: Presuppositions and Implications of a New Approach in Biology

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The scientists’ perception of how science policy conceptualizes and assesses systems biology is contrasted with that of societal actors. Our analysis shows that the discourses in these fields are interconnected; they influence each other and mutually interact. Results coming from this analysis relate to the identity of systems biology as a new science, to the similarity of the scientific and public images of what systems biology is, and to the sustainability of funding. Although participation of the general public in the discussion is seen as important by politics and the media, it does not seem to be important for scientists.

This aspect becomes visible in the conceptual metaphors used to frame mental activity. Jäkel (1997, 184–188) has shown that mental activity has been depicted in conventional metaphors such as IDEAS ARE OBJECTS, THINKING IS WORKING ON PROBLEM-OBJECTS WITH THE MIND-TOOL, or FORMING IDEAS IS SHAPING RAW MATERIAL whereas doing science has been metaphorically framed in terms of SCIENCE IS A JOURNEY or as SCIENCE IS THE STRUGGLE FOR THE SURVIVAL OF THE FITTEST. These conceptual metaphors develop coherent models or so-called cognitive models that represent experiential simplifications of an even more complex reality and at the same time provide a semantic structure which pervades scientific thought and practice.

It follows that some images are more accessible than others in the sense that they conform more to experimental results than others. Furthermore it seems that the aspects of accuracy and comprehensibility are directly related to the important aspect of conventionality. What becomes thus apparent in the previous examples is the fact that the channel metaphor is rather easy to understand and it is nowadays an integral part in research. Lakoff and Johnson (1980) stated that scientific discourses are replete with and based on so-called conventional metaphors which semantically structure their content.

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